Vetoquinol Zylkene Plus Long-Term Calming Supplement, 225 mg for Cats and Dogs 22-65 lbs.

Zylkene Plus is a long-term calming supplement with a dual-action formula to promote relaxation in pets over longer periods. 

The behavior supplement includes alpha-casozepine and white fish muscle hydrolysate, which is naturally rich in bioactive marine peptides and supports adaptation, resilience, and cognitive function. 

Zylkene Plus is:

• Made with high-quality ingredients
• Backed by real-world evidence¹
• Lactose free
• Non-sedating
• Proven palatability and ease of administration²

Zylkene Plus helps promote calm and relaxed behavior when a pet’s routine is altered in situations such as: 

• A new baby
• A new pet
• Moving
• Left home alone 

Vetoquinol stands behind its products with a 100% satisfaction guarantee or your money back. Try it today! 

Zylkene Plus carries the quality seal of the National Animal Supplement Council. To display the NASC Quality Seal on our products, we undergo regular and rigorous audits to ensure we’re manufacturing only the highest-quality supplements for pets.

Made in the USA with globally sourced ingredients.

Capsules can be administered once daily, whole or opened. Can be given during or after mealtime. 

Zylkene Plus 225mg:

• Dogs 22-32 lbs: 1 capsule daily
• Dogs 33-65 lbs: 2 capsules daily
• Cats: 1 capsule daily or as recommended by a veterinarian 

Zylkene Plus is available in 30-count bottles.

1. Porcheron, G., Bodet, M., Poiron, K., Brault, J., Massal, N., Roy, O., & Fantini, O. (2023). Supplementation Effects of an Alpha-Casozepine and White Fish Muscle Hydrolyzed Complementary Feed on Canine Separation-Related Disorders and Quality of Life of Dogs and Their Pet Caregivers. Open Journal of Veterinary Medicine, 13(6), Article 6. 
2. Data on file, Vetoquinol.